The glucocerobrosidase E326K variant predisposes to Parkinson's disease, but does not cause Gaucher's disease
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IGF-1 LR3 Research Applications The most established application of IGF-1 LR3 is as a growth factor supplement in serum-free mammalian cell culture, where Morris and Schmid (Biotechnology Progress, 2000) compared LongR3 against insulin in CHO lines expressing recombinant proteins, and where it is widely used as an insulin replacement at much lower concentrations